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1

How to Identify a Pharmacophore

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 77 KB

english, 2008

2

Molecular Basis of Drug Interaction with L-Type Ca2+Channels

Jörg Mitterdorfer, Manfred Grabner, Richard L. Kraus, Steffen Hering, Heino Prinz, Hartmut Glossmann, Jörg Striessnig

Journal:

Journal of Bioenergetics and Biomembranes

Year:

1998

Language:

english

File:

PDF, 2.49 MB

english, 1998

3

Tailored Surface-Enhanced Raman Nanopillar Arrays Fabricated by Laser-Assisted Replication for Biomolecular Detection Using Organic Semiconductor Lasers

Liu, Xin, Lebedkin, Sergei, Besser, Heino, Pfleging, Wilhelm, Prinz, Stephan, Wissmann, Markus, Schwab, Patrick M., Nazarenko, Irina, Guttmann, Markus, Kappes, Manfred M., Lemmer, Uli

Journal:

Year:

2015

Language:

english

File:

PDF, 5.36 MB

english, 2015

4

Synthesis of Nucleopeptides by Employing an Enzyme-Labile Urethane Protecting Group

Duraiswamy A. Jeyaraj, Heino Prinz, Herbert Waldmann

Journal:

Chemistry - A European Journal

Year:

2002

Language:

english

File:

PDF, 557 KB

english, 2002

5

Total Synthesis and Reassessment of the Phosphatase-Inhibitory Activity of the Antitumor Agent TMC-69-6H

Alois Fürstner, Fabian Feyen, Heino Prinz, Herbert Waldmann

Journal:

Angewandte Chemie

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

6

Eine Mikroarray-Strategie zur Untersuchung der Substratspezifitäten von Protein-Tyrosin-Phosphatasen

Maja Köhn, Marta Gutierrez-Rodriguez, Pascal Jonkheijm, Stefan Wetzel, Ron Wacker, Hendrik Schroeder, Heino Prinz, Christof M. Niemeyer, Rolf Breinbauer, Stefan E. Szedlacsek, Herbert Waldmann

Journal:

Angewandte Chemie

Year:

2007

Language:

german

File:

PDF, 467 KB

german, 2007

7

Total Synthesis and Reassessment of the Phosphatase-Inhibitory Activity of the Antitumor Agent TMC-69-6H

Alois Fürstner, Fabian Feyen, Heino Prinz, Herbert Waldmann

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

8

A Microarray Strategy for Mapping the Substrate Specificity of Protein Tyrosine Phosphatase

Maja Köhn, Marta Gutierrez-Rodriguez, Pascal Jonkheijm, Stefan Wetzel, Ron Wacker, Hendrik Schroeder, Heino Prinz, Christof M. Niemeyer, Rolf Breinbauer, Stefan E. Szedlacsek, Herbert Waldmann

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 462 KB

english, 2007

9

The Core Structures of Roseophilin and the Prodigiosin Alkaloids Define a New Class of Protein Tyrosine Phosphatase Inhibitors

Alois Fürstner, Kerstin Reinecke, Heino Prinz, Herbert Waldmann

Journal:

Year:

2004

Language:

english

File:

PDF, 194 KB

english, 2004

10

Discovery of Mycobacterium Tuberculosis Protein Tyrosine Phosphatase A (MptpA) Inhibitors Based on Natural Products and a Fragment-Based Approach

Michael Manger, Michael Scheck, Heino Prinz, Jens Peter von Kries, Thomas Langer, Krishna Saxena, Harald Schwalbe, Alois Fürstner, Jörg Rademann, Herbert Waldmann

Journal:

Year:

2005

Language:

english

File:

PDF, 103 KB

english, 2005

11

ChemInform Abstract: Synthesis of Nucleopeptides by Employing an Enyzme-Labile Urethane Protecting Group.

Duraiswamy A. Jeyaraj, Heino Prinz, Herbert Waldmann

Journal:

Year:

2002

File:

PDF, 23 KB

2002

12

Total Synthesis and Reassessment of the Phosphatase-Inhibitory Activity of the Antitumor Agent TMC-69-6H.

Alois Fuerstner, Fabian Feyen, Heino Prinz, Herbert Waldmann

Journal:

Year:

2004

File:

PDF, 62 KB

2004

13

Structure Assignment, Total Synthesis, and Evaluation of the Phosphatase Modulating Activity of Glucolipsin A.

Alois Fuerstner, Juliana Ruiz-Caro, Heino Prinz, Herbert Waldmann

Journal:

Year:

2004

File:

PDF, 65 KB

2004

14

Synthesis and Evaluation of the Antitumor Agent TMC-69-6H and a Focused Library of Analogues.

Alois Fuerstner, Fabian Feyen, Heino Prinz, Herbert Waldmann

Journal:

Year:

2005

File:

PDF, 11 KB

2005

15

Drosophila photoreceptors express cysteine peptidase tan

Stefanie Wagner, Christiane Heseding, Kamila Szlachta, John R. True, Heino Prinz, Bernhard T. Hovemann

Journal:

The Journal of Comparative Neurology

Year:

2007

Language:

english

File:

PDF, 1.19 MB

english, 2007

16

3-Substituted indolizine-1-carbonitrile derivatives as phosphatase inhibitors

Timo Weide, Lars Arve, Heino Prinz, Herbert Waldmann, Horst Kessler

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 163 KB

english, 2006

17

Synthesis and evaluation of the antitumor agent TMC-69-6H and a focused library of analogs

Alois Fürstner, Fabian Feyen, Heino Prinz, Herbert Waldmann

Journal:

Year:

2004

Language:

english

File:

PDF, 546 KB

english, 2004

18

Substrate binding modes and anomer selectivity of chitinase A fromVibrio harveyi

Wipa Suginta, Supansa Pantoom, Heino Prinz

Journal:

Journal of Chemical Biology

Year:

2009

Language:

english

File:

PDF, 415 KB

english, 2009

19

Transient binding patches: a plausible concept for drug binding

Heino Prinz, André Schönichen

Journal:

Journal of Chemical Biology

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

20

Hill coefficients, dose–response curves and allosteric mechanisms

Journal:

Journal of Chemical Biology

Year:

2010

Language:

english

File:

PDF, 329 KB

english, 2010

21

Simplification traps

Journal:

Journal of Chemical Biology

Year:

2012

Language:

english

File:

PDF, 179 KB

english, 2012

22

Enzymatic properties of wild-type and active site mutants of chitinase A from Vibrio carchariae, as revealed by HPLC-MS

Wipa Suginta, Archara Vongsuwan, Chomphunuch Songsiriritthigul, Jisnuson Svasti, Heino Prinz

Journal:

Year:

2005

Language:

english

File:

PDF, 242 KB

english, 2005

23

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

Hakkim, Abdul, Fuchs, Tobias A, Martinez, Nancy E, Hess, Simone, Prinz, Heino, Zychlinsky, Arturo, Waldmann, Herbert

Journal:

Nature Chemical Biology

Year:

2010

Language:

english

File:

PDF, 576 KB

english, 2010

24

Loss of smell leads to dementia in mice: Is Alzheimer's disease a degenerative disorder of the olfactory system?

Peter Kurtz, T. Schuurman, Heino Prinz

Journal:

The Protein Journal

Year:

1989

Language:

english

File:

PDF, 243 KB

english, 1989

25

Synthesis and properties of NBD-n-acylcholines, fluorescent analogs of acetylcholine

Hans-Wilhelm MEYERS, Rolf JÜRSS, Hans R. BRENNER, Gregor FELS, Heino PRINZ, Heidrun WATZKE, Alfred MAELICKE

Journal:

Year:

1983

Language:

english

File:

PDF, 625 KB

english, 1983

26

Structure Assignment, Total Synthesis, and Evaluation of the Phosphatase Modulating Activity of Glucolipsin A

Fürstner, Alois, Ruiz-Caro, Juliana, Prinz, Heino, Waldmann, Herbert

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 224 KB

english, 2004

27

Numerical Methods for the Life Scientist Volume 599 || Fitting the Data

Year:

2011

Language:

english

File:

PDF, 1.90 MB

english, 2011

28

Drosophila ACT88F indirect flight muscle-specific actin is not N-terminally acetylated: a mutation in N-terminal processing affects actin function

Stephan Schmitz, Jonathan Clayton, Upendra Nongthomba, Heino Prinz, Claudia Veigel, Michael Geeves, John Sparrow

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 250 KB

english, 2000

29

Spermine stabilizes the conformation of tRNAPhe in crystals

Heino Prinz, Nazli Furgac, Friedrich Cramer

Journal:

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis

Year:

1976

Language:

english

File:

PDF, 345 KB

english, 1976

30

Ligand-specific state transitions of the membrane-bound acetylcholine receptor

Manuel Covarrubias, Heino Prinz, Alfred Maelicke

Journal:

Year:

1984

Language:

english

File:

PDF, 509 KB

english, 1984

31

An endochitinase A from Vibrio carchariae: cloning, expression, mass and sequence analyses, and chitin hydrolysis

Wipa Suginta, Archara Vongsuwan, Chomphunuch Songsiriritthigul, Heino Prinz, Peter Estibeiro, Rory R Duncan, Jisnuson Svasti, Linda A Fothergill-Gilmore

Journal:

Archives of Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 1.30 MB

english, 2004

32

cAPK-phosphorylation controls the interaction of the regulatory domain of cardiac myosin binding protein C with myosin-S2 in an on-off fashion

Mathias Gruen, Heino Prinz, Mathias Gautel

Journal:

Year:

1999

Language:

english

File:

PDF, 213 KB

english, 1999

33

One hundred percent online identity check of pharmaceutical products by near-infrared spectroscopy on the packaging line

Thorsten Herkert, Heino Prinz, Karl-Artur Kovar

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2001

Language:

english

File:

PDF, 508 KB

english, 2001

34

Numerical Methods for the Life Scientist || Enzyme Kinetics

Year:

2011

Language:

english

File:

PDF, 2.08 MB

english, 2011

35

Synthesis, Characterization, and Application of Cy-Dye- and Alexa-Dye-Labeled Hongotoxin 1 Analogues. The First High Affinity Fluorescence Probes for Voltage-Gated K + Channels

Pragl, Bernt, Koschak, Alexandra, Trieb, Maria, Obermair, Gerald, Kaufmann, Walter A., Gerster, Uli, Blanc, Eric, Hahn, Christoph, Prinz, Heino, Schütz, Gerhard, Darbon, Herve, Gruber, Hermann J., Kna

Journal:

Bioconjugate Chemistry

Year:

2002

Language:

english

File:

PDF, 457 KB

english, 2002

36

Numerical Methods for the Life Scientist ||

Year:

2011

Language:

english

File:

PDF, 11.39 MB

english, 2011

37

Brunsvicamides A−C: Sponge-Related Cyanobacterial Peptides with Mycobacterium tuberculosis Protein Tyrosine Phosphatase Inhibitory Activity

Müller, Daniela, Krick, Anja, Kehraus, Stefan, Mehner, Christian, Hart, Mark, Küpper, Frithjof C., Saxena, Krishna, Prinz, Heino, Schwalbe, Harald, Janning, Petra, Waldmann, Herbert, König, Gabriele M

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 97 KB

english, 2006

38

The Kinetic Mechanism of Ran-Nucleotide Exchange Catalyzed by RCC1

Klebe, Christian, Prinz, Heino, Wittinghofer, Alfred, Goody, Roger S.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.17 MB

english, 1995

39

Accelerated disassembly of IgE–receptor complexes by a disruptive macromolecular inhibitor

Kim, Beomkyu, Eggel, Alexander, Tarchevskaya, Svetlana S., Vogel, Monique, Prinz, Heino, Jardetzky, Theodore S.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

40

Agonist binding to the nicotinic acetylcholine receptor and probability of channel opening

Journal:

Neurochemistry International

Year:

1988

Language:

english

File:

PDF, 1.05 MB

english, 1988

41

NBD-5-Acylcholine: Fluorescent Analog of Acetylcholine and Agonist at the Neuromuscular Junction

Rolf Jürss, Heino Prinz and Alfred Maelicke

Journal:

Proceedings of the National Academy of Sciences

Year:

1979

Language:

english

File:

PDF, 1.15 MB

english, 1979

42

Unfolding of yeast transfer ribonucleic acid species caused by addition of organic solvents and studied by circular dichroism

Prinz, Heino, Maelicke, Alfred, Cramer, Friedrich

Journal:

Year:

1974

Language:

english

File:

PDF, 474 KB

english, 1974

43

Kinetic Analysis by Fluorescence of the Interaction between Ras and the Catalytic Domain of the Guanine Nucleotide Exchange Factor Cdc25 Mm †

Lenzen, Christian, Cool, Robbert H., Prinz, Heino, Kuhlmann, Jürgen, Wittinghofer, Alfred

Journal:

Year:

1998

Language:

english

File:

PDF, 141 KB

english, 1998

44

Ligand binding to the membrane-bound acetylcholine receptor from Torpedo marmorata: a complete mathematical analysis

Prinz, Heino, Maelicke, Alfred

Journal:

Year:

1992

Language:

english

File:

PDF, 1.22 MB

english, 1992

45

Optimization of Three- and Four-Component Reactions for Polysubstituted Piperidines: Application to the Synthesis and Preliminary Biological Screening of a Prototype Library

Ulaczyk-Lesanko, Agnieszka, Pelletier, Eric, Lee, Maria, Prinz, Heino, Waldmann, Herbert, Hall, Dennis G.

Journal:

Journal of Combinatorial Chemistry

Year:

2007

Language:

english

File:

PDF, 309 KB

english, 2007

46

L-Type Calcium Channels: Binding Domains for Dihydropyridines and Benzothiazepines Are Located in Close Proximity to Each Other †

Brauns, Thomas, Prinz, Heino, Kimball, S. David, Haugland, Richard P., Striessnig, Jörg, Glossmann, Hartmut

Journal:

Year:

1997

Language:

english

File:

PDF, 172 KB

english, 1997

47

Complex Molecular Mechanism for Dihydropyridine Binding to L-Type Ca2+-Channels As Revealed by Fluorescence Resonance Energy Transfer

Berger, Wolfgang, Prinz, Heino, Striessnig, Joerg, Kang, Hee-Chol, Haugland, Richard, Glossmann, Hartmut

Journal:

Year:

1994

Language:

english

File:

PDF, 1.09 MB

english, 1994

48

Polyketides from the marine-derived fungus Ascochyta salicorniae and their potential to inhibit protein phosphatases

Seibert, Simon F., Eguereva, Ekaterina, Krick, Anja, Kehraus, Stefan, Voloshina, Elena, Raabe, Gerhard, Fleischhauer, J?rg, Leistner, Eckhard, Wiese, Michael, Prinz, Heino, Alexandrov, Kirill, Janning

Journal:

Organic & Biomolecular Chemistry

Year:

2006

Language:

english

File:

PDF, 202 KB

english, 2006

49

On the Interpretation of Equilibrium Binding Studies

Journal:

Journal of Receptor and Signal Transduction Research

Year:

1983

Language:

english

File:

PDF, 312 KB

english, 1983

50

Organic semiconductor distributed feedback laser pixels for lab-on-a-chip applications fabricated by laser-assisted replication

Liu, Xin, Prinz, Stephan, Besser, Heino, Pfleging, Wilhelm, Wissmann, Markus, Vannahme, Christoph, Guttmann, Markus, Mappes, Timo, Koeber, Sebastian, Koos, Christian, Lemmer, Uli

Journal:

Faraday Discussions

Year:

2014

Language:

english

File:

PDF, 1.00 MB

english, 2014